解:原式$=\frac{1}{4}×(5-1)(5+1)(5^2+1)(5^4+1)(5^8+1)(5^{16}+1)+\frac{1}{4}$
$=\frac{1}{4}×(5^2-1)(5^2+1)(5^4+1)(5^8+1)(5^{16}+1)+\frac{1}{4}$
$=\frac{1}{4}×(5^4-1)(5^4+1)(5^8+1)(5^{16}+1)+\frac{1}{4}$
$=\frac{1}{4}×(5^8-1)(5^8+1)(5^{16}+1)+\frac{1}{4}$
$=\frac{1}{4}×(5^{16}-1)(5^{16}+1)+\frac{1}{4}$
$=\frac{1}{4}×(5^{32}-1)+\frac{1}{4}$
$=\frac{5^{32}}{4}$